Profhilo 2ml

(1 customer review)

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Profhilo 2ml — Profhilo Bio-remodelling injectable (hybrid HA). NAHYCO Bio-Remodelling · 64 mg/2ml Hybrid HA · BDDE-Free. For licensed healthcare professionals only.

$115.00

Quantity discounts
Quantity Discount Price
5-93%$111.55
10-195%$109.25
20-Unlimited8%$105.80
64
mg / 2ml
Total HA
32+32
mg
H-HA + L-HA
BDDE
free
Thermal NAHYCO
5+5
BAP
Bio Aesthetic Points
Product Overview

What is Profhilo 2ml?

Profhilo 2ml is IBSA’s injectable bio-remodelling treatment built on NAHYCO Hybrid Technology — one of the highest HA concentrations available at 64 mg per 2 mL syringe (32 mg high-molecular-weight H-HA + 32 mg low-molecular-weight L-HA). It is stabilised thermally without BDDE chemical cross-linkers and is used to treat skin laxity, hydration and elasticity of the face and neck. Lidocaine-free; CE marked.

Profhilo created the bio-remodelling category: rather than filling lines or adding volume, the hybrid cooperative complex spreads through the tissue from a small number of Bio Aesthetic Points (BAP) and slowly releases HA, stimulating collagen and elastin and improving tissue quality. The combination of two molecular weights gives high spreadability with a single 29G needle, and the BDDE-free thermal stabilisation supports a low-inflammatory profile.

Composition

Profhilo 2ml Key Ingredients

Structure & lift

HIGH-MW HA (H-HA)

32 mg · 1100–1400 kDa
High-molecular-weight hyaluronic acid, 32 mg per 2 mL.

Provides longer residence in tissue and the slow-release reservoir that drives the lifting and tightening effect over the weeks following treatment.

Hydration & diffusion

LOW-MW HA (L-HA)

32 mg · 80–100 kDa
Low-molecular-weight hyaluronic acid, 32 mg per 2 mL.

Delivers intense hydration and high spreadability, allowing wide tissue coverage from a small number of injection points.

Thermal stabilisation

NAHYCO COMPLEX

Hybrid cooperative · BDDE-free
Stable hybrid cooperative complex formed by a patented thermal process.

Binds H-HA and L-HA without chemical cross-linking agents, giving a fluid, manageable gel (tan delta > 1) distinct from cross-linked fillers.

Indications

What Profhilo 2ml Treats

Skin laxity of the face (cheeks, jawline)
Neck remodelling and tightening
Loss of elasticity and firmness
Crepey, dehydrated or ageing skin
Overall skin-quality and tone improvement
Adjunct to other aesthetic and filler protocols
Specifications

Profhilo 2ml Specifications

Product
Profhilo 2ml (H+L)
Brand
Profhilo (IBSA)
Category
Bio-remodelling injectable (hybrid HA)
Total HA
64 mg per 2 mL syringe
Composition
32 mg H-HA (1100–1400 kDa) + 32 mg L-HA (80–100 kDa)
Technology
NAHYCO Hybrid Technology — BDDE-free thermal process
Lidocaine
None
Presentation
1 × 2 mL pre-filled syringe
Technique
Bio Aesthetic Points (BAP) — 5 per side / 10 on neck
Protocol
2 sessions 4 weeks apart; maintenance ~6 months
Storage
2–25 °C, do not freeze
Certification
CE marked medical device
FAQ

Profhilo 2ml — Frequently Asked Questions

Is Profhilo a filler or a skinbooster?

Neither in the traditional sense. Profhilo opened a separate category called bio-remodelling. It is not designed to fill lines or add volume, but to remodel and tighten tissue while delivering intense hydration through a hybrid HA complex.

What is in Profhilo 2ml?

64 mg of hyaluronic acid per 2 mL syringe — 32 mg of high-molecular-weight H-HA and 32 mg of low-molecular-weight L-HA, bound by IBSA’s NAHYCO thermal process. It is BDDE-free and lidocaine-free.

What does BDDE-free mean?

Most cross-linked HA gels are stabilised with the chemical agent BDDE. Profhilo instead uses a patented thermal process (NAHYCO) to stabilise the hybrid complex without chemical cross-linkers.

How is Profhilo injected?

Using the Bio Aesthetic Points (BAP) technique — typically 5 points on each side of the face, or 10 points on the neck. The high spreadability allows wide coverage from few injection sites.

How many sessions are needed?

The standard protocol is two treatments four weeks apart, with maintenance generally around every six months. Individual plans are at the practitioner’s discretion.

How long does it last?

Skin continues to improve over the weeks after treatment as collagen and elastin are stimulated; maintenance is commonly advised at about six months. Longevity varies by patient.

Which areas can be treated?

Most commonly the face, neck, décolletage and hands. Profhilo is suitable for patients showing signs of skin laxity who are appropriate candidates for HA treatment.

Who should administer it?

Profhilo is a CE-marked medical device for use by trained, licensed medical and aesthetic practitioners only.

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Important Safety Information

Read Before Clinical Use

Profhilo 2ml is a CE-marked medical device for licensed practitioners only. Expected reactions include injection-site redness, swelling, bruising and tenderness at the Bio Aesthetic Points. As with all HA injectables, rare vascular complications are possible; aseptic technique and anatomical knowledge are essential. It is lidocaine-free. Consult the manufacturer Instructions for Use for full contraindications, warnings, precautions and aftercare guidance.

Last reviewed: May 2026. Sources: manufacturer official product information and verified regulatory data.

Regulatory Notice: PROFHILO and NAHYCO are registered trademarks of IBSA Institut Biochimique SA. MJS Medicals is a distributor and is not liable for clinical outcomes. Regulatory status varies by jurisdiction — buyers are responsible for verifying local regulations. Informational content only — not medical advice.

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1 review
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1 review for Profhilo 2ml

Clear filters
    Lucas Johnson
    2026-06-18
    The biggest advantage is how natural it looks. Unlike fillers that change facial structure, this just improves skin quality without making it obvious you’ve had any treatment.
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