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Restylane Kysse
RESTYLANE® KYSSE with Lidocaine is a specialized hyaluronic acid dermal filler designed for precise lip augmentation and perioral rejuvenation. Utilizing Optimal Balance Technology™, it provides natural-looking volume with 85% patient satisfaction and reduced swelling. Contains 3mg/ml lidocaine for enhanced comfort. Results typically last 6-9 months.
$118.90
Restylane Kysse — Galderma OBT Lip-Dedicated HA Filler with Lidocaine
What it is
Restylane Kysse is Galderma’s lip-dedicated OBT-technology filler — specifically engineered for natural lip volumising, lip border definition, lip texture refinement, and upper lip wrinkles. The OBT monophasic structure preserves natural lip movement and expression while delivering volume correction. Soft enough for mucosa, firm enough to define lip border.
How OBT / XpresHAn (lip-optimised) Technology works
Galderma Optimal Balance Technology (XpresHAn globally) — lip-optimized OBT variant tuned for soft natural movement and color preservation in lip mucosa.
Technical specifications
Detail for clinical, regulatory, and shipping reference.
| HA Source | Streptococcus equi bacterial fermentation, non-animal origin |
| Cross-linker | BDDE |
| Technology | OBT / XpresHAn (lip-optimised variant) |
| Gel Structure | Monophasic |
| Lip-Specific Properties | Color stability, expression flexibility, mucosa cohesion |
| Manufacturer | Galderma / Q-Med AB |
| Origin | Uppsala, Sweden |
| CE Mark | CE marked |
| Storage | 2–25 °C · do not freeze · protect from direct sunlight |
| Shelf life | 24 months unopened (verify lot label) |
| Reversibility | Dissolvable with hyaluronidase if needed |
| Intended use | Licensed medical professionals only |
FAQ
Why use Kysse instead of standard Restylane for lips?+
Standard Restylane (NASHA) can be used in lips but is firmer and more palpable. Kysse is OBT-technology specifically tuned for lip mucosa — softer, more cohesive, blends with lip tissue rather than sitting as discrete particles. Kysse also has superior color stability in lips and is designed to flex with kissing, smiling, and speaking. For lip-specific work, Kysse is the dedicated tool in Galderma’s portfolio.
How long does this product last?+
Duration is Up to 12 months in lips depending on injection site, patient metabolism, and lifestyle. Mobile facial zones (lips, perioral) typically resorb faster than static zones (cheek, temple). Individual hyaluronidase activity influences longevity.
What’s the storage requirement?+
Standard HA filler storage at 2–25 °C (room temperature acceptable). Do not freeze. Protect from direct sunlight. No cold-chain shipping required (this is not a botulinum toxin). 24-month shelf life unopened; verify lot label before use.
Where to buy wholesale and verify authenticity?+
Wholesale through MJS Medicals for licensed healthcare professionals. Verify authenticity: (1) intact tamper-evident sterile seal; (2) batch number with manufacturer traceability label; (3) HA concentration matches 20 mg/mL on packaging; (4) origin marking visible; (5) certification visible on box.
Who is qualified to inject?+
Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with HA filler-specific training only. Buyers self-certify professional status at checkout.
Safety
This product-specific: Lip mucosa is highly vascular — labial artery runs behind the wet-dry border. Aspirate before each injection; cannula technique preferred in deep lip body. Lip-specific complications: vascular occlusion in labial artery network, asymmetry, lumpiness if placed too superficially.
Prescription medical device. Contraindicated in known hypersensitivity to HA, lidocaine, or Gram-positive bacterial proteins; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune disorders; active local infection; concurrent anticoagulant therapy. Aspirate before injection; keep hyaluronidase on hand for reversal.
Last reviewed: May 2026 · Source verification: Manufacturer official documentation · Multi-distributor cross-check
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