Restylane Refyne Lidocaine 1ml

(1 customer review)

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Discover Restylane Refyne, a premium 20 mg/mL hyaluronic acid filler featuring advanced XpresHAn Technology. Expertly designed for dynamic facial areas, it visibly smooths nasolabial folds and marionette lines while maintaining completely natural facial expressions, offering exceptional aesthetic results that can last for up to 12 months.

$129.00

Quantity discounts
Quantity Discount Price
5-93%$125.13
10-195%$122.55
20-Unlimited8%$118.68

Restylane Refyne Lidocaine 1ml — Galderma OBT/XpresHAn Soft HA Filler

HA Concentration
20 mg/mL
Lidocaine
0.3% (3 mg/mL) premixed
Pack
1 × 1.0 mL
Needles
30G ½”
Depth
Mid dermal
Duration
Up to 12 months
Indications
Mid-depth NLF · Perioral lines · Marionettes
Technology
OBT / XpresHAn — Standard 2–25 °C storage · No cold-chain shipping required (this is not a botulinum toxin)

What it is

Restylane Refyne is the softest OBT-technology gel in Galderma’s Restylane portfolio — formulated for mid-depth facial wrinkles, fine-to-moderate nasolabial folds, marionette lines, and perioral wrinkles. The flexible monophasic gel structure yields with facial expression rather than restricting it, ideal for dynamic zones around the mouth.

How OBT / XpresHAn Technology works

Galderma Optimal Balance Technology (XpresHAn globally) — softest OBT gel in the Restylane range, engineered for natural movement in expression-heavy facial zones.

Technical specifications

Detail for clinical, regulatory, and shipping reference.

HA Source Streptococcus equi bacterial fermentation, non-animal origin
Cross-linker BDDE
Technology OBT / XpresHAn (softest in range)
Gel Structure Monophasic
Manufacturer Galderma / Q-Med AB
Origin Uppsala, Sweden
CE Mark CE marked
Storage 2–25 °C · do not freeze · protect from direct sunlight
Shelf life 24 months unopened (verify lot label)
Reversibility Dissolvable with hyaluronidase if needed
Intended use Licensed medical professionals only

FAQ

When should I choose Restylane Refyne over Defyne?+

Choose Refyne for softer, more dynamic correction. Refyne suits early-to-moderate NLF, perioral fine lines, smile lines, and patients who prioritize natural expression. Defyne is medium-firmness for deeper wrinkles and chin augmentation. A common combo: Refyne for marionette and perioral lines + Defyne for deep NLF in the same session.

How long does this product last?+

Duration is Up to 12 months depending on injection site, patient metabolism, and lifestyle. Mobile facial zones (lips, perioral) typically resorb faster than static zones (cheek, temple). Individual hyaluronidase activity influences longevity.

What’s the storage requirement?+

Standard HA filler storage at 2–25 °C (room temperature acceptable). Do not freeze. Protect from direct sunlight. No cold-chain shipping required (this is not a botulinum toxin). 24-month shelf life unopened; verify lot label before use.

Where to buy wholesale and verify authenticity?+

Wholesale through MJS Medicals for licensed healthcare professionals. Verify authenticity: (1) intact tamper-evident sterile seal; (2) batch number with manufacturer traceability label; (3) HA concentration matches 20 mg/mL on packaging; (4) origin marking visible; (5) certification visible on box.

Who is qualified to inject?+

Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with HA filler-specific training only. Buyers self-certify professional status at checkout.

Safety

This product-specific: Mid-dermal placement around perioral zone — careful depth control to avoid Tyndall effect (bluish discoloration). Standard vascular precautions for nasolabial branches.

Prescription medical device. Contraindicated in known hypersensitivity to HA, lidocaine, or Gram-positive bacterial proteins; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune disorders; active local infection; concurrent anticoagulant therapy. Aspirate before injection; keep hyaluronidase on hand for reversal.

→ Full Dermal Filler Safety Information

Last reviewed: May 2026 · Source verification: Manufacturer official documentation · Multi-distributor cross-check
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1 review for Restylane Refyne Lidocaine 1ml

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    Tyler Brooks
    2026-06-05
    I was hesitating about getting my nasolabial folds (smile lines) filled because some friends looked a bit stiff when smiling after their treatments. This time, on my doctor's recommendation, I chose Restylane Refyne, which is specifically designed for dynamic wrinkles. It's been about two weeks since I got it, and I'm really surprised by the results. The hyaluronic acid blended perfectly. When I laugh or make exaggerated expressions, it looks super natural, without that "fake face" feel at all. It contains numbing medicine, so aside from a little pressure during the injection, I barely felt any pain. I'll definitely keep repurchasing this one.
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