Restylane Defyne Lidocaine 1ml

(1 customer review)

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Restylane is a globally renowned hyaluronic acid filler designed to create natural, dynamic facial contours. Its precise formula, with a hyaluronic acid concentration of 20 mg/ml, utilizes innovative XPresHAn Technology™, allowing just 1 ml to seamlessly integrate with facial tissue, effectively smoothing deep wrinkles, lifting the jawline, and maintaining natural, fluid facial expressions. This advanced formula prioritizes client comfort, incorporating 0.3% lidocaine to ensure a smooth and comfortable injection process.

$121.80

Quantity discounts
Quantity Discount Price
5-93%$118.15
10-195%$115.71
20-Unlimited8%$112.06

Restylane Defyne Lidocaine 1ml — Galderma OBT/XpresHAn HA Filler

HA Concentration
20 mg/mL
Lidocaine
0.3% (3 mg/mL) premixed
Pack
1 × 1.0 mL
Needles
27G ½”
Depth
Mid-to-deep dermal
Duration
Up to 12 months
Indications
Deep NLF · Marionettes · Chin augmentation
Technology
OBT / XpresHAn — Standard 2–25 °C storage · No cold-chain shipping required (this is not a botulinum toxin)

What it is

Restylane Defyne is Galderma’s medium-firmness OBT / XpresHAn-Technology filler — designed for deep facial wrinkles including nasolabial folds, marionette lines, and chin augmentation. The OBT monophasic gel structure provides volume correction while preserving natural facial expression. 0.3% premixed lidocaine reduces injection discomfort.

How OBT / XpresHAn Technology works

Galderma Optimal Balance Technology (XpresHAn globally) — monophasic gel engineered for flexibility with facial movement while delivering structural correction.

Technical specifications

Detail for clinical, regulatory, and shipping reference.

HA Source Streptococcus equi bacterial fermentation, non-animal origin
Cross-linker BDDE
Technology OBT (Optimal Balance Technology) / XpresHAn
Gel Structure Monophasic
Manufacturer Galderma / Q-Med AB
Origin Uppsala, Sweden
CE Mark CE marked for international markets
Storage 2–25 °C · do not freeze · protect from direct sunlight
Shelf life 24 months unopened (verify lot label)
Reversibility Dissolvable with hyaluronidase if needed
Intended use Licensed medical professionals only

FAQ

How is Restylane Defyne different from Refyne?+

Both use OBT / XpresHAn Technology but differ in firmness. Refyne is softer / more flexible — for mid-depth wrinkles, perioral lines, dynamic expression zones. Defyne is medium-firmness — for deeper wrinkles, more pronounced NLF, marionettes, chin augmentation. Choose Refyne for softer expression-preserving correction; Defyne for stronger structural support.

How long does this product last?+

Duration is Up to 12 months depending on injection site, patient metabolism, and lifestyle. Mobile facial zones (lips, perioral) typically resorb faster than static zones (cheek, temple). Individual hyaluronidase activity influences longevity.

What’s the storage requirement?+

Standard HA filler storage at 2–25 °C (room temperature acceptable). Do not freeze. Protect from direct sunlight. No cold-chain shipping required (this is not a botulinum toxin). 24-month shelf life unopened; verify lot label before use.

Where to buy wholesale and verify authenticity?+

Wholesale through MJS Medicals for licensed healthcare professionals. Verify authenticity: (1) intact tamper-evident sterile seal; (2) batch number with manufacturer traceability label; (3) HA concentration matches 20 mg/mL on packaging; (4) origin marking visible; (5) certification visible on box.

Who is qualified to inject?+

Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with HA filler-specific training only. Buyers self-certify professional status at checkout.

Safety

This product-specific: Deep dermal placement near nasolabial and perioral facial artery branches. Aspirate before injection; cannula technique recommended in vascular zones. Pregnancy / breastfeeding: insufficient safety data, contraindicated.

Prescription medical device. Contraindicated in known hypersensitivity to HA, lidocaine, or Gram-positive bacterial proteins; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune disorders; active local infection; concurrent anticoagulant therapy. Aspirate before injection; keep hyaluronidase on hand for reversal.

→ Full Dermal Filler Safety Information

Last reviewed: May 2026 · Source verification: Manufacturer official documentation · Multi-distributor cross-check
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1 review for Restylane Defyne Lidocaine 1ml

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    Lucas Harrington
    2026-05-29
    Works exactly as it should. It's my favorite filler to work with for clients who are very expressive. The lidocaine makes the whole process smoother for the patient, which makes my job easier. Quality is spot on, will buy again.
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