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Juvederm Ultra Smile (2 x 0.55ml)
Juvederm Ultra Smile is a hyaluronic acid dermal filler containing 24 mg/ml HA and 0.3% lidocaine, clinically proven to enhance lip volume (92% satisfaction at 6 months) and reduce vertical lip lines. Results last up to 12 months, with 68% less injection discomfort due to integrated anesthetic. Ideal for natural-looking lip augmentation and perioral rejuvenation, for precise contouring and hydration.
$153.00
Juvederm Ultra Smile 2×0.55ml — Allergan Hylacross HA Lip Filler with Lidocaine
What it is
Ultra Smile is Allergan’s dedicated lip-augmentation product within the Hylacross range — formulated specifically for lip body volumization, vermilion border definition, and perioral fine-line correction. The 0.55 mL syringe size and 30G fine-gauge needles are optimized for the precision required in delicate lip work.
How Hylacross Technology works
Hylacross Technology (smooth cohesive HA, lip-optimized formulation). Hylacross is Allergan’s foundational cross-linking process — producing a highly cohesive, smooth monophasic gel with predictable injection flow and excellent tissue integration. Hylacross HA is fully biodegradable, broken down naturally by the body over 9–12 months.
Technical specifications
Detail for clinical, regulatory, and shipping reference. Headline figures shown in the panel above.
| Manufacturer | Allergan Aesthetics (AbbVie subsidiary) |
| Manufacturing Origin | Haute Savoie, France |
| HA Source | Streptococcus equi bacterial fermentation, non-animal origin |
| Cross-linker | BDDE · Hylacross Technology |
| Excipients | Phosphate buffer pH 7.2 |
| Volumizing Capacity | 3/5 |
| CE Mark | 0459 Class III medical device |
| Storage | 2–25 °C · do not freeze · protect from direct sunlight |
| Shelf life | 24 months unopened (verify lot label) |
| Reversibility | Dissolvable with hyaluronidase if needed |
| Intended use | Licensed medical professionals only |
FAQ
How is Ultra Smile different from Volbella for lip work?+
Both are lip-optimized Juvederm products. Ultra Smile (Hylacross, 24 mg/mL HA) provides more volume and projection — suited for lip body augmentation and patients wanting noticeably fuller lips. Volbella (Vycross, 15 mg/mL HA) is softer and more subtle — suited for delicate vermilion border definition and barely-there perioral line correction. Practitioners often stock both for different patient preferences.
Where is Juvederm manufactured?+
Juvederm is manufactured by Allergan Aesthetics (an AbbVie subsidiary) at their facility in Haute Savoie, France. This is the original Allergan production site for the global Juvederm range, including the Hylacross-based Ultra collection. CE 0459 Class III medical device certification.
How long does this product last?+
Duration is Up to 12 months depending on injection site, patient metabolism, and lifestyle. Mobile facial zones (lips, perioral) typically resorb faster than static zones (cheek, temple). Individual hyaluronidase activity also influences longevity.
What’s the difference between Hylacross and Vycross technology?+
Both are Allergan-proprietary HA cross-linking technologies. Hylacross (used in the Ultra range) is the foundational process producing a smooth cohesive monophasic gel — best known for predictable injection flow and tissue integration. Vycross (used in Voluma/Volbella/Volift/Volux/Volite) is the newer technology combining low and high molecular weight HA chains for higher cross-linking efficiency, lower HA concentration, and longer duration. Vycross products generally last longer (12–18 months) than Hylacross products (up to 12 months).
Where to buy wholesale and how to verify authenticity?+
Wholesale through MJS Medicals for licensed healthcare professionals. To verify authenticity: (1) Allergan / Juvederm branding on packaging with Haute Savoie France origin marking; (2) CE 0459 mark visible; (3) HA concentration matches 24 mg/mL; (4) batch number with traceability labels included per box; (5) intact tamper-evident sterile seal; (6) French / English language packaging.
Who is qualified to inject?+
Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with Juvederm-specific training only. Allergan provides global injector training programs. Buyers self-certify professional status at checkout.
Safety
This product-specific: Lip mucosa is highly vascular — labial artery runs just behind the wet-dry border. Aspirate before injection; cannula technique preferred in deep lip body. The 30G needles included are specifically gauge-matched for precision lip work.
Prescription medical device (CE 0459 Class III). Contraindicated in known hypersensitivity to HA, lidocaine, or Gram-positive bacterial proteins; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune disorders; active local infection; and concurrent anticoagulant therapy. Aspirate before injection; keep hyaluronidase on hand for reversal. Vision abnormalities (rare but serious) have been reported in some Juvederm products — strict avoidance of off-label injection into highly vascular areas (glabella, periorbital, nose) required.
Last reviewed: May 2026 · Source verification: hcp.juvederm.com · Allergan Aesthetics · CE 0459 Class III · ISO 13485:2016
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